Ube2a ubiquitin-conjugating enzyme E2A [ Mus musculus (house mouse) ] - Gene - Data resources

22209

Ube2a ubiquitin-conjugating enzyme E2A [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 22209)

Symbol: Ube2a

Full name: ubiquitin-conjugating enzyme E2A

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: HHR6A; HR6A; Mhr6a

Summary: Enables ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Acts upstream of or within blastocyst hatching; maternal process involved in female pregnancy; and protein ubiquitination. Located in XY body and chromatin. Is expressed in several structures, including alimentary system; brain; female reproductive system; integumental system; and respiratory system. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Nascimento type. Orthologous to human UBE2A (ubiquitin conjugating enzyme E2 A). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in placenta adult (RPKM 13.3), CNS E18 (RPKM 11.1) and 28 other tissues

Orthologs: human

Gene size: 9928bp

Exon count: 6