THSD7A thrombospondin type 1 domain containing 7A [ Homo sapiens (human) ]
Source: NCBI Gene (ID 221981)
Source: NCBI Gene (ID 221981)
Symbol: THSD7A
Full name: thrombospondin type 1 domain containing 7A
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Summary: The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis. [provided by RefSeq, Aug 2010]
Expression: Broad expression in kidney (RPKM 4.1), placenta (RPKM 2.1) and 17 other tissues
Orthologs: mouse
Gene size: 461834bp
Exon count: 30