Full name: T cell leukemia, homeobox 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Enx; Hox11L.1; Hox11l1; NCX; Ncx1; Tlx1l1; Tlx1l2

Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within enteric nervous system development; mesoderm formation; and negative regulation of dendrite morphogenesis. Located in cytoplasm and nucleus. Is expressed in several structures, including adrenal gland; alimentary system; nervous system; primitive streak; and urethra. Used to study intestinal pseudo-obstruction. Orthologous to human TLX2 (T cell leukemia homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in adrenal adult (RPKM 24.6), duodenum adult (RPKM 3.7) and 4 other tissues

Gene size: 1901bp

Exon count: 3