Full name: talin 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Tln

Summary: Enables integrin binding activity; phosphatidylinositol binding activity; and phosphatidylserine binding activity. Involved in integrin activation and integrin-mediated signaling pathway. Acts upstream of or within cell-substrate junction assembly and cortical actin cytoskeleton organization. Located in focal adhesion. Is expressed in several structures, including body cavity or lining; cardiovascular system; neural plate; submandibular gland; and vertebral axis musculature. Orthologous to human TLN1 (talin 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in spleen adult (RPKM 86.9), ovary adult (RPKM 82.7) and 28 other tissues

Gene size: 31071bp

Exon count: 60