Full name: TAO kinase 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2810468K05Rik; D130018F14Rik; Map3k16; Markk; Psk2

Summary: Predicted to enable several functions, including cytoskeletal protein binding activity; protein C-terminus binding activity; and protein serine/threonine kinase activator activity. Predicted to be involved in several processes, including intracellular signal transduction; positive regulation of JNK cascade; and regulation of cytoskeleton organization. Predicted to act upstream of or within DNA repair and apoptotic process. Predicted to be located in microtubule cytoskeleton and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including adrenal gland; alimentary system; lung; nervous system; and retina. Orthologous to human TAOK1 (TAO kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E18 (RPKM 7.8), frontal lobe adult (RPKM 7.6) and 28 other tissues

Gene size: 96198bp

Exon count: 24