Full name: TEA domain family member 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2610024B07Rik; B230114H05Rik; Gtrgeo5; TEAD-1; TEF-1; Tcf13; mTEF-1

Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; cellular response to retinoic acid; and hippo signaling. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; musculature; and tooth. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Orthologous to human TEAD1 (TEA domain transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in bladder adult (RPKM 16.6), heart adult (RPKM 14.4) and 24 other tissues

Gene size: 227429bp

Exon count: 14