Full name: thymine DNA glycosylase

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: E130317C12Rik; JZA-3; Jza1

Summary: Enables several functions, including SUMO binding activity; protein kinase C binding activity; and transcription coregulator activity. Involved in DNA metabolic process; regulation of embryonic development; and regulation of gene expression, epigenetic. Acts upstream of or within negative regulation of chromatin binding activity; negative regulation of protein binding activity; and negative regulation of transcription by RNA polymerase II. Located in PML body. Is expressed in several structures, including epithelium; genitourinary system; nervous system; retina; and skin. Orthologous to human TDG (thymine DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E11.5 (RPKM 41.6), CNS E14 (RPKM 32.7) and 28 other tissues

Gene size: 20985bp

Exon count: 10