Full name: upstream binding transcription factor, RNA polymerase I

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: A930005G04Rik; NOR-90; Tcfubf; UBF; UBF-1; UBF1

Summary: Predicted to enable several functions, including RNA polymerase I general transcription initiation factor activity; RNA polymerase I transcription regulatory region sequence-specific DNA binding activity; and scaffold protein binding activity. Involved in positive regulation of transcription by RNA polymerase I. Acts upstream of or within cellular response to leukemia inhibitory factor; rDNA heterochromatin assembly; and transcription elongation from RNA polymerase I promoter. Located in nucleolus. Is expressed in several structures, including brain; branchial arch; early conceptus; genitourinary system; and limb. Orthologous to human UBTF (upstream binding transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E11.5 (RPKM 28.0), liver E14 (RPKM 15.9) and 28 other tissues

Gene size: 19353bp

Exon count: 25