Full name: adaptor-related protein complex 1 associated regulatory protein

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Gadkin

Summary: Predicted to enable AP-1 adaptor complex binding activity; Arp2/3 complex binding activity; and kinesin binding activity. Acts upstream of or within several processes, including negative regulation of cell motility; negative regulation of substrate adhesion-dependent cell spreading; and regulation of Arp2/3 complex-mediated actin nucleation. Located in endosome. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; integumental system; and nervous system. Orthologous to human AP1AR (adaptor related protein complex 1 associated regulatory protein). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in duodenum adult (RPKM 18.9), colon adult (RPKM 18.9) and 28 other tissues

Gene size: 30517bp

Exon count: 13