Full name: transformation related protein 53 binding protein 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 53BP2; ASPP2; PPP1R13A; Tp53bp2

Summary: Predicted to enable NF-kappaB binding activity; identical protein binding activity; and p53 binding activity. Acts upstream of or within several processes, including embryo development; heart development; and response to ionizing radiation. Predicted to be located in cell junction and cytosol. Predicted to be active in nucleus. Predicted to colocalize with perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study chromosome 1q41-q42 deletion syndrome. Orthologous to human TP53BP2 (tumor protein p53 binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in lung adult (RPKM 11.1), CNS E11.5 (RPKM 10.0) and 28 other tissues

Gene size: 53270bp

Exon count: 18