Gen1 GEN1, Holliday junction 5' flap endonuclease [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 209334)
Source: NCBI Gene (ID 209334)
Symbol: Gen1
Full name: GEN1, Holliday junction 5' flap endonuclease
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 5830483C08Rik
Summary: Predicted to enable several functions, including endodeoxyribonuclease activity; magnesium ion binding activity; and protein homodimerization activity. Predicted to be involved in DNA metabolic process and regulation of cell cycle process. Predicted to act upstream of or within DNA repair. Predicted to be located in centrosome. Is expressed in embryo; nephric duct; and neural tube. Orthologous to human GEN1 (GEN1 Holliday junction 5' flap endonuclease). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in liver E14 (RPKM 2.5), CNS E11.5 (RPKM 2.1) and 12 other tissues
Orthologs: human
Gene size: 27102bp
Exon count: 18