Sucla2 succinate-Coenzyme A ligase, ADP-forming, beta subunit [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 20916)
Source: NCBI Gene (ID 20916)
Symbol: Sucla2
Full name: succinate-Coenzyme A ligase, ADP-forming, beta subunit
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 4930547K18Rik; A-SCS; SCS-betaA
Summary: Predicted to enable succinate-CoA ligase (ADP-forming) activity and succinate-CoA ligase (GDP-forming) activity. Predicted to be involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study mitochondrial DNA depletion syndrome 5. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 5. Orthologous to human SUCLA2 (succinate-CoA ligase ADP-forming subunit beta). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in heart adult (RPKM 50.4), testis adult (RPKM 42.5) and 26 other tissues
Orthologs: human
Gene size: 43359bp
Exon count: 11