Wdr11 WD repeat domain 11 [ Mus musculus (house mouse) ] - Gene - Data resources

207425

Wdr11 WD repeat domain 11 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 207425)

Symbol: Wdr11

Full name: WD repeat domain 11

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2900055P10Rik; Brwd2; mKIAA1351

Summary: Involved in several processes, including cilium assembly; heart development; and regulation of smoothened signaling pathway. Located in axoneme; ciliary basal body; and nucleus. Is expressed in several structures, including central nervous system; frontal bone primordium; metanephros; otic capsule; and submandibular gland primordium. Used to study Kallmann syndrome and ciliopathy. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 14 with or without anosmia. Orthologous to human WDR11 (WD repeat domain 11). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in limb E14.5 (RPKM 10.9), CNS E11.5 (RPKM 9.5) and 28 other tissues

Orthologs: human

Gene size: 44090bp

Exon count: 29