Sphk1 sphingosine kinase 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 20698)
Source: NCBI Gene (ID 20698)
Symbol: Sphk1
Full name: sphingosine kinase 1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Mus musculus
Also known as: 1110006G24Rik; Sk1; Spk1
Summary: This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Expression: Broad expression in lung adult (RPKM 8.3), duodenum adult (RPKM 6.9) and 25 other tissues
Orthologs: human
Gene size: 5841bp
Exon count: 8