Six4 sine oculis-related homeobox 4 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 20474)
Source: NCBI Gene (ID 20474)
Symbol: Six4
Full name: sine oculis-related homeobox 4
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: AREC3; TrexBF
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; positive regulation of morphogenesis of an epithelium; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including embryonic organ morphogenesis; myoblast migration; and thymus development. Located in cytoplasm and nucleus. Is expressed in several structures, including exocrine gland; nervous system; sensory organ; tongue; and urinary system. Orthologous to human SIX4 (SIX homeobox 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in limb E14.5 (RPKM 2.1), CNS E11.5 (RPKM 1.4) and 15 other tissues
Orthologs: human
Gene size: 14423bp
Exon count: 4