Siah1a siah E3 ubiquitin protein ligase 1A [ Mus musculus (house mouse) ] - Gene - Data resources

20437

Siah1a siah E3 ubiquitin protein ligase 1A [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 20437)

Symbol: Siah1a

Full name: siah E3 ubiquitin protein ligase 1A

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Sinh1a

Summary: Enables several functions, including disordered domain specific binding activity; protein homodimerization activity; and zinc ion binding activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Acts upstream of or within male gamete generation; post-embryonic development; and regulation of growth. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including alimentary system; early embryo; gonad; hemolymphoid system gland; and liver. Orthologous to human SIAH1 (siah E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in whole brain E14.5 (RPKM 8.3), CNS E14 (RPKM 8.0) and 28 other tissues

Orthologs: human

Gene size: 30185bp

Exon count: 3