Sfrp4 secreted frizzled-related protein 4 [ Mus musculus (house mouse) ] - Gene - Data resources

20379

Sfrp4 secreted frizzled-related protein 4 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 20379)

Symbol: Sfrp4

Full name: secreted frizzled-related protein 4

Gene type: protein coding

RefSeq status: VALIDATED

Summary: Predicted to enable Wnt-protein binding activity. Involved in bone morphogenesis; negative regulation of Wnt signaling pathway; and regulation of BMP signaling pathway. Predicted to be located in cell surface and nucleus. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; brain; eye; lung; and urinary system. Human ortholog(s) of this gene implicated in metaphyseal dysplasia. Orthologous to human SFRP4 (secreted frizzled related protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in ovary adult (RPKM 372.4) and subcutaneous fat pad adult (RPKM 17.6)

Orthologs: human

Gene size: 9651bp

Exon count: 6