EIF5 eukaryotic translation initiation factor 5 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 1983)
Symbol: EIF5
Full name: eukaryotic translation initiation factor 5
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: EIF-5; EIF-5A
Summary: Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]
Expression: Ubiquitous expression in bone marrow (RPKM 60.5), thyroid (RPKM 44.5) and 25 other tissues
Orthologs: mouse
Gene size: 10789bp
Exon count: 13