EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 1979)
Source: NCBI Gene (ID 1979)
Symbol: EIF4EBP2
Full name: eukaryotic translation initiation factor 4E binding protein 2
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: 4EBP2; PHASII
Summary: This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]
Expression: Ubiquitous expression in fat (RPKM 50.2), kidney (RPKM 34.8) and 25 other tissues
Orthologs: mouse
Gene size: 24474bp
Exon count: 3