Full name: RAN, member RAS oncogene family

Gene type: protein coding

RefSeq status: VALIDATED

Summary: Predicted to enable several functions, including dynein intermediate chain binding activity; guanyl ribonucleotide binding activity; and importin-alpha family protein binding activity. Predicted to contribute to pre-miRNA binding activity. Acts upstream of or within actin cytoskeleton organization; protein import into nucleus; and protein-containing complex localization. Located in cytoplasm and nuclear envelope. Is expressed in several structures, including branchial arch; central nervous system; extraembryonic component; hemolymphoid system gland; and sensory organ. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human RAN (RAN, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E11.5 (RPKM 161.6), liver E14 (RPKM 152.8) and 28 other tissues

Gene size: 4167bp

Exon count: 7