Rad50 RAD50 double strand break repair protein [ Mus musculus (house mouse) ] - Gene - Data resources

19360

Rad50 RAD50 double strand break repair protein [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 19360)

Symbol: Rad50

Full name: RAD50 double strand break repair protein

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Mrell; Rad50l

Summary: Predicted to enable DNA binding activity; identical protein binding activity; and protein-macromolecule adaptor activity. Predicted to contribute to 3'-5' exonuclease activity; DNA helicase activity; and single-stranded DNA endodeoxyribonuclease activity. Acts upstream of or within chromosome organization involved in meiotic cell cycle and regulation of mitotic cell cycle. Located in pronucleus. Is expressed in several structures, including aorta; hemolymphoid system gland; liver; lung; and testis. Human ortholog(s) of this gene implicated in transitional cell carcinoma. Orthologous to human RAD50 (RAD50 double strand break repair protein). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in bladder adult (RPKM 4.4), CNS E11.5 (RPKM 4.2) and 28 other tissues

Orthologs: human

Gene size: 57801bp

Exon count: 25