Dusp1 dual specificity phosphatase 1 [ Mus musculus (house mouse) ] - Gene - Data resources

19252

Dusp1 dual specificity phosphatase 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 19252)

Symbol: Dusp1

Full name: dual specificity phosphatase 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 3CH134; MKP1; Ptpn16; erp; mkp-1

Summary: Enables mitogen-activated protein kinase binding activity and phosphoprotein phosphatase activity. Involved in negative regulation of MAPK cascade; negative regulation of cell population proliferation; and protein dephosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human DUSP1 (dual specificity phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in lung adult (RPKM 117.9), heart adult (RPKM 43.4) and 28 other tissues

Orthologs: human

Gene size: 2882bp

Exon count: 4