Full name: pleiotrophin

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: HARP; HB-GAM; HBBM; HBBN; HBGF-8; HBNF; OSF; Osf-1; Osf1

Summary: Predicted to enable several functions, including glycosaminoglycan binding activity; signaling receptor binding activity; and syndecan binding activity. Involved in several processes, including decidualization; learning or memory; and regulation of nervous system development. Acts upstream of or within bone mineralization. Located in extracellular region. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in adrenal carcinoma. Orthologous to human PTN (pleiotrophin). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in CNS E18 (RPKM 106.8), frontal lobe adult (RPKM 95.9) and 7 other tissues

Gene size: 95256bp

Exon count: 6