Full name: HIG1 hypoxia inducible domain family member 2A

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: RCF1b

Summary: The protein encoded by this gene is a subunit of the cytochrome c oxidase complex (complex IV), which is the terminal enzyme in the mitochondrial respiratory chain. The encoded protein is an inner mitochondrial membrane protein and is a functional ortholog of the yeast respiratory supercomplex factor 1 (Rcf1). In mouse, the orthologous protein enhances cell survival under conditions of hypoxia. [provided by RefSeq, Sep 2016]

Expression: Ubiquitous expression in heart (RPKM 70.3), colon (RPKM 67.0) and 25 other tissues

Gene size: 1011bp

Exon count: 2