Ptgir prostaglandin I receptor (IP) [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 19222)
Symbol: Ptgir
Full name: prostaglandin I receptor (IP)
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: IP; PGI2
Summary: Predicted to enable prostacyclin receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of platelet-derived growth factor receptor signaling pathway; and negative regulation of smooth muscle cell proliferation. Acts upstream of or within response to lipopolysaccharide. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; gallbladder; genitourinary system; hemolymphoid system gland; and limb segment. Orthologous to human PTGIR (prostaglandin I2 receptor). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in mammary gland adult (RPKM 4.9), spleen adult (RPKM 4.5) and 19 other tissues
Orthologs: human
Gene size: 4416bp
Exon count: 2