Full name: proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: GT198; HOP2; Tbpip

Summary: Predicted to enable several functions, including DNA binding domain binding activity; nuclear receptor binding activity; and nuclear receptor coactivator activity. Predicted to be involved in meiosis I and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within DNA recombination and meiotic cell cycle. Predicted to be located in nucleoplasm. Predicted to be part of DNA recombinase auxiliary factor complex. Predicted to be active in condensed nuclear chromosome. Is expressed in metanephros; submandibular gland primordium; telencephalon ventricular layer; tooth; and vibrissa. Human ortholog(s) of this gene implicated in ovarian dysgenesis 3. Orthologous to human PSMC3IP (PSMC3 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in testis adult (RPKM 36.1), CNS E11.5 (RPKM 17.1) and 11 other tissues

Gene size: 5024bp

Exon count: 7