Full name: G protein-coupled receptor 143

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Oa1

Summary: Predicted to enable L-DOPA receptor activity; amino acid binding activity; and dopamine binding activity. Involved in regulation of melanosome organization and regulation of melanosome transport. Predicted to be located in several cellular components, including apical plasma membrane; lysosomal membrane; and melanosome. Predicted to be active in melanosome membrane and plasma membrane. Is expressed in several structures, including eye; hair follicle; and inner ear. Used to study ocular albinism. Human ortholog(s) of this gene implicated in congenital nystagmus 6. Orthologous to human GPR143 (G protein-coupled receptor 143). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Low expression observed in reference dataset

Gene size: 26731bp

Exon count: 9