Full name: natriuretic peptide type C

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CNP; lbab

Summary: This gene encodes a member of the natriuretic peptide family. Natriuretic peptides are involved in the control of blood pressure, extracellular fluid volume and electrolyte homeostasis. The encoded protein also plays a role in sensory neuron bifurcation, and is a critical regulator of endochondral bone growth. The encoded protein is a ligand for the natriuretic peptide receptor B, and is synthesized as a preprohormone which is cleaved to produce a mature peptide. Mutations in this gene are associated with dwarfism resulting from impaired endochondral ossification. [provided by RefSeq, Apr 2011]

Expression: Biased expression in ovary adult (RPKM 20.5), cerebellum adult (RPKM 4.7) and 7 other tissues

Gene size: 4281bp

Exon count: 3