Full name: dopamine receptor D2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: D2DR; D2R

Summary: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]

Expression: Biased expression in adrenal (RPKM 4.1), endometrium (RPKM 0.7) and 3 other tissues

Gene size: 65794bp

Exon count: 9