Full name: nerve growth factor receptor (TNFR superfamily, member 16)

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: LNGFR; Tnfrsf16; p75; p75NGFR; p75NTR

Summary: Enables death receptor activity; nerve growth factor binding activity; and small GTPase binding activity. Involved in several processes, including cellular glucose homeostasis; circadian regulation of gene expression; and dorsal aorta development. Acts upstream of or within several processes, including hair follicle morphogenesis; nervous system development; and regulation of signal transduction. Located in several cellular components, including cell surface; cell-cell junction; and postsynaptic density. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and mental depression. Orthologous to human NGFR (nerve growth factor receptor). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in subcutaneous fat pad adult (RPKM 31.4), ovary adult (RPKM 24.6) and 20 other tissues

Gene size: 18881bp

Exon count: 6