DNASE1L3 deoxyribonuclease 1 like 3 [ Homo sapiens (human) ] - Gene - Data resources

1776

DNASE1L3 deoxyribonuclease 1 like 3 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 1776)

Symbol: DNASE1L3

Full name: deoxyribonuclease 1 like 3

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DHP2; DNAS1L3; LSD; SLEB16

Summary: This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

Expression: Biased expression in spleen (RPKM 118.4), liver (RPKM 61.9) and 11 other tissues

Orthologs: mouse

Gene size: 18716bp

Exon count: 8