Full name: multiple PDZ domain crumbs cell polarity complex component

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: B930003D11Rik; MUPP1

Summary: Predicted to enable protein C-terminus binding activity. Involved in dendrite development and intracellular protein transport. Acts upstream of or within cell adhesion. Located in several cellular components, including Schmidt-Lanterman incisure; apical plasma membrane; and bicellular tight junction. Part of subapical complex. Is active in synapse. Is expressed in several structures, including central nervous system; early conceptus; olfactory epithelium; and retina. Human ortholog(s) of this gene implicated in hydrocephalus. Orthologous to human MPDZ (multiple PDZ domain crumbs cell polarity complex component). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in CNS E11.5 (RPKM 10.3), limb E14.5 (RPKM 8.8) and 22 other tissues

Gene size: 164377bp

Exon count: 48