Mllt10 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 17354)
Source: NCBI Gene (ID 17354)
Symbol: Mllt10
Full name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Af10; B130021D15Rik; D630001B22Rik; mKIAA4140
Summary: Predicted to enable histone binding activity and nucleosome binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; early conceptus; genitourinary system; limb; and maxillary process. Human ortholog(s) of this gene implicated in acute monocytic leukemia and acute myeloid leukemia. Orthologous to human MLLT10 (MLLT10 histone lysine methyltransferase DOT1L cofactor). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in testis adult (RPKM 23.6), thymus adult (RPKM 9.8) and 28 other tissues
Orthologs: human
Gene size: 157231bp
Exon count: 30