Full name: septin 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DIFF6; LARP; PNUTL3; SEP1; SEPT1

Summary: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Expression: Biased expression in lymph node (RPKM 27.2), spleen (RPKM 18.3) and 9 other tissues

Gene size: 4681bp

Exon count: 12