Mgrn1 mahogunin, ring finger 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 17237)
Symbol: Mgrn1
Full name: mahogunin, ring finger 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 2610042J20Rik; mKIAA0544; md; nc
Summary: Enables ubiquitin protein ligase activity. Involved in negative regulation of smoothened signaling pathway. Acts upstream of or within protein polyubiquitination. Predicted to be located in endoplasmic reticulum. Predicted to be active in early endosome; nucleus; and plasma membrane. Is expressed in several structures, including genitourinary system; heart; node; and skin. Orthologous to human MGRN1 (mahogunin ring finger 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in heart adult (RPKM 66.4), ovary adult (RPKM 57.2) and 28 other tissues
Orthologs: human
Gene size: 52197bp
Exon count: 20