DHODH dihydroorotate dehydrogenase (quinone) [ Homo sapiens (human) ]
Source: NCBI Gene (ID 1723)
Source: NCBI Gene (ID 1723)
Symbol: DHODH
Full name: dihydroorotate dehydrogenase (quinone)
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: DHOdehase; POADS; URA1
Summary: The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in liver (RPKM 7.8), kidney (RPKM 1.7) and 24 other tissues
Orthologs: mouse
Gene size: 18916bp
Exon count: 10