Full name: minichromosome maintenance complex component 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: BM28; CDCL1; Mcmd2; mKIAA0030

Summary: Enables DNA replication origin binding activity; enzyme binding activity; and histone binding activity. Acts upstream of or within DNA unwinding involved in DNA replication; cellular response to interleukin-4; and nucleosome assembly. Located in nucleus. Part of nuclear origin of replication recognition complex. Is expressed in several structures, including central nervous system; future brain; inner cell mass; limb; and vertebral axis musculature. Human ortholog(s) of this gene implicated in Alzheimer's disease and autosomal dominant nonsyndromic deafness 70. Orthologous to human MCM2 (minichromosome maintenance complex component 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in liver E14.5 (RPKM 77.8), liver E14 (RPKM 74.1) and 21 other tissues

Gene size: 15307bp

Exon count: 16