Mbd2 methyl-CpG binding domain protein 2 [ Mus musculus (house mouse) ] - Gene - Data resources

17191

Mbd2 methyl-CpG binding domain protein 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 17191)

Symbol: Mbd2

Full name: methyl-CpG binding domain protein 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: MBD2a

Summary: Enables chromatin binding activity and nucleic acid binding activity. Acts upstream of or within several processes, including maternal behavior; negative regulation of transcription by RNA polymerase II; and positive regulation of Wnt signaling pathway. Located in cytoplasm; heterochromatin; and nucleus. Part of histone deacetylase complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; limb ectoderm; and retina. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MBD2 (methyl-CpG binding domain protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in bladder adult (RPKM 26.7), liver E14 (RPKM 24.5) and 28 other tissues

Orthologs: human

Gene size: 60472bp

Exon count: 9