Mapkapk5 MAP kinase-activated protein kinase 5 [ Mus musculus (house mouse) ] - Gene - Data resources

17165

Mapkapk5 MAP kinase-activated protein kinase 5 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 17165)

Symbol: Mapkapk5

Full name: MAP kinase-activated protein kinase 5

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: MK5; PRAK

Summary: Enables mitogen-activated protein kinase binding activity; p53 binding activity; and protein serine/threonine kinase activity. Involved in Ras protein signal transduction; negative regulation of TOR signaling; and stress-induced premature senescence. Acts upstream of or within positive regulation of dendritic spine development. Located in cytoplasm; nucleus; and septin cytoskeleton. Part of protein-containing complex. Is expressed in brain; embryo; and lung. Orthologous to human MAPKAPK5 (MAPK activated protein kinase 5). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E11.5 (RPKM 21.0), CNS E14 (RPKM 20.7) and 28 other tissues

Orthologs: human

Gene size: 20842bp

Exon count: 14