Full name: alpha-methylacyl-CoA racemase

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Macr1

Summary: Predicted to enable alpha-methylacyl-CoA racemase activity and signaling receptor binding activity. Predicted to be involved in bile acid biosynthetic process. Predicted to act upstream of or within isoprenoid catabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; cranium; genitourinary system; liver; and respiratory system. Used to study alpha-methylacyl-CoA racemase deficiency. Human ortholog(s) of this gene implicated in alpha-methylacyl-CoA racemase deficiency; congenital bile acid synthesis defect 4; and urinary bladder cancer. Orthologous to human AMACR (alpha-methylacyl-CoA racemase). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in liver adult (RPKM 25.9), kidney adult (RPKM 22.2) and 25 other tissues

Gene size: 14869bp

Exon count: 5