Alad aminolevulinate, delta-, dehydratase [ Mus musculus (house mouse) ] - Gene - Data resources

17025

Alad aminolevulinate, delta-, dehydratase [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 17025)

Symbol: Alad

Full name: aminolevulinate, delta-, dehydratase

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: ALADH; Lv

Summary: Enables identical protein binding activity and porphobilinogen synthase activity. Acts upstream of or within cellular response to interleukin-4 and heme biosynthetic process. Predicted to be located in extracellular space. Predicted to be active in cytosol. Is expressed in several structures, including liver; lung; metanephros; spleen; and yolk sac. Human ortholog(s) of this gene implicated in porphyria cutanea tarda and sickle cell anemia. Orthologous to human ALAD (aminolevulinate dehydratase). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in liver E14.5 (RPKM 66.3), liver E14 (RPKM 56.6) and 27 other tissues

Orthologs: human

Gene size: 14080bp

Exon count: 13