Full name: LIF receptor alpha

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: A230075M04Rik; LIF

Summary: Predicted to enable several functions, including ciliary neurotrophic factor receptor binding activity; growth factor binding activity; and leukemia inhibitory factor receptor activity. Predicted to contribute to ciliary neurotrophic factor receptor activity and oncostatin-M receptor activity. Acts upstream of or within positive regulation of cell population proliferation. Predicted to be located in extracellular region and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and immune system. Used to study CAKUT. Human ortholog(s) of this gene implicated in osteochondrodysplasia. Orthologous to human LIFR (LIF receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in placenta adult (RPKM 14.4), liver adult (RPKM 13.6) and 23 other tissues

Gene size: 106880bp

Exon count: 25