Lama4 laminin, alpha 4 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 16775)
Symbol: Lama4
Full name: laminin, alpha 4
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Summary: Predicted to enable signaling receptor binding activity. Predicted to be an extracellular matrix structural constituent. Involved in negative regulation of cold-induced thermogenesis. Acts upstream of or within blood vessel development and brown fat cell differentiation. Located in basement membrane and neuromuscular junction. Is active in synaptic cleft. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1JJ. Orthologous to human LAMA4 (laminin subunit alpha 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in bladder adult (RPKM 25.5), subcutaneous fat pad adult (RPKM 21.8) and 19 other tissues
Orthologs: human
Gene size: 144674bp
Exon count: 38