DCP2 decapping mRNA 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 167227)
Symbol: DCP2
Full name: decapping mRNA 2
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: NUDT20
Summary: The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
Expression: Ubiquitous expression in lymph node (RPKM 7.7), placenta (RPKM 6.8) and 24 other tissues
Orthologs: mouse
Gene size: 45398bp
Exon count: 12