Full name: F11 receptor

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 9130004G24; ESTM33; JAM; JAM-1; JAM-A; Jcam; Jcam1; Ly106

Summary: Predicted to enable PDZ domain binding activity; integrin binding activity; and protein homodimerization activity. Involved in intestinal absorption; regulation of cytokine production; and regulation of membrane permeability. Acts upstream of or within cell adhesion and epithelial cell differentiation. Located in bicellular tight junction. Is expressed in several structures, including 4-8 cell stage embryo; alimentary system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in large intestine adult (RPKM 80.5), lung adult (RPKM 57.6) and 21 other tissues

Gene size: 27033bp

Exon count: 10