Itk IL2 inducible T cell kinase [ Mus musculus (house mouse) ] - Gene - Data resources

16428

Itk IL2 inducible T cell kinase [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 16428)

Symbol: Itk

Full name: IL2 inducible T cell kinase

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Emt; Tcsk; Tsk

Summary: Predicted to enable non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including T cell receptor signaling pathway; activation of phospholipase C activity; and gamma-delta T cell activation. Acts upstream of or within NK T cell differentiation. Located in cell-cell junction and nucleus. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 1. Orthologous to human ITK (IL2 inducible T cell kinase). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in thymus adult (RPKM 35.8), spleen adult (RPKM 4.7) and 1 other tissue

Orthologs: human

Gene size: 64368bp

Exon count: 18