Full name: Iroquois homeobox 2

Gene type: protein coding

RefSeq status: VALIDATED

Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within proximal/distal pattern formation involved in metanephric nephron development and specification of loop of Henle identity. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; autopod; central nervous system; genitourinary system; and respiratory system. Orthologous to human IRX2 (iroquois homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in lung adult (RPKM 35.9), mammary gland adult (RPKM 23.4) and 9 other tissues

Gene size: 10853bp

Exon count: 6