DGKA diacylglycerol kinase alpha [ Homo sapiens (human) ]
Source: NCBI Gene (ID 1606)
Source: NCBI Gene (ID 1606)
Symbol: DGKA
Full name: diacylglycerol kinase alpha
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: DAGK; DAGK1; DGK-alpha
Summary: The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Apr 2017]
Expression: Broad expression in lymph node (RPKM 36.2), skin (RPKM 31.7) and 19 other tissues
Orthologs: mouse
Gene size: 22862bp
Exon count: 32