Idua iduronidase, alpha-L [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 15932)
Source: NCBI Gene (ID 15932)
Symbol: Idua
Full name: iduronidase, alpha-L
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 6030426D08
Summary: Enables L-iduronidase activity. Acts upstream of or within several processes, including glycosaminoglycan catabolic process; learning or memory; and skeletal system development. Located in extracellular space. Used to study mucopolysaccharidosis I and otitis media. Human ortholog(s) of this gene implicated in Scheie syndrome; mucopolysaccharidosis I; mucopolysaccharidosis Ih; and mucopolysaccharidosis Ih/s. Orthologous to human IDUA (alpha-L-iduronidase). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in ovary adult (RPKM 10.1), adrenal adult (RPKM 10.0) and 28 other tissues
Orthologs: human
Gene size: 25116bp
Exon count: 15