Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 15360)
Symbol: Hmgcs2
Full name: 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 1300002P16; mHS
Summary: Enables hydroxymethylglutaryl-CoA synthase activity. Predicted to be involved in acetyl-CoA metabolic process; farnesyl diphosphate biosynthetic process, mevalonate pathway; and ketone body biosynthetic process. Predicted to act upstream of or within cholesterol biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; facial bone primordium; nervous system; and reproductive system. Orthologous to human HMGCS2 (3-hydroxy-3-methylglutaryl-CoA synthase 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in liver E18 (RPKM 447.3), liver adult (RPKM 391.9) and 3 other tissues
Orthologs: human
Gene size: 30308bp
Exon count: 10